Students in Dr. Emily Day’s research group have published a paper in the International Journal of Nanomedicine describing a new way to sensitize cancer cells to chemotherapy. Chemotherapy resistance in cancer is often attributed to cancer cells’ ability to keep drugs outside the cell. The Day lab has shown that this resistance mechanism can be overcome by heating cancer cells with photothermal therapy, a technique in which nanoparticles delivered to cancer cells produce heat upon exposure to light. The Day lab’s results demonstrate that applying heat to cancer cells with photothermal therapy can increase drug accumulation in the cells, which in turn improves treatment effect. The student co-authors on the paper include Brittany Fay, who received her B.S. in Biomedical Engineering at UD in May 2015, and Jilian Melamed, current Biomedical Engineering Ph.D. student. This research was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), by the Delaware INBRE program with a grant from NIGMS of the NIH, by the University of Delaware Summer Scholars Program, and by the Department of Defense through a National Defense Science and Engineering Graduate Fellowship.
- Revolutionizing prostheticsUD research aims to improve the lives of those with limb loss.
- Renaissance womanLauren Mottel, a first-year biomedical engineering doctoral student and UD engineering alumna, is the recipient of the 2024 Laird Fellowship.
- A new molecular understanding of protein phase separationUD researcher Kristi Kiick is part of a new study that provides insights into how disordered proteins form membrane-free liquid droplets, with implications for cell biology research, developing new disease treatments, and designing novel biomaterials.
- Bio-inspired innovationsApril Kloxin has been inducted to the 2024 College of Fellows of the American Institute for Medical and Biological Engineering.
- Doctoral Dissertation Defense – Margo DonlinBME PhD Candidate Margo Donlin will be defending their dissertation: Adaptive Post-Stroke Gait Rehabilitation Methods To Increase Propulsion