A paper co-authored by Emily Day, “miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma”, has been selected as the cover of an upcoming issue of Genes & Development. The paper identifies a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor. The researchers used nanoparticles called spherical nucleic acids to safely deliver miR-182 across the blood-brain/blood-tumor barriers to reach tumor cells where they directly suppressed multiple oncogenes at once, increasing cancer cell death, reducing tumor growth, and improving overall survival. This approach offers a novel strategy for therapeutic intervention in GBM.
- Doctoral Dissertation Defense – Róisín B. DonnellyDate: September 10th, 2024, 9:00 am (EST) Location: AP Bio 140
- Doctoral Dissertation Defense – Harrah NewmanDate and Time: Thursday August 22nd, 9AM Non-Invasive Evaluation of In Vivo Intervertebral Disc Mechanical Function
- Revolutionizing prostheticsUD research aims to improve the lives of those with limb loss.
- Renaissance womanLauren Mottel, a first-year biomedical engineering doctoral student and UD engineering alumna, is the recipient of the 2024 Laird Fellowship.
- A new molecular understanding of protein phase separationUD researcher Kristi Kiick is part of a new study that provides insights into how disordered proteins form membrane-free liquid droplets, with implications for cell biology research, developing new disease treatments, and designing novel biomaterials.