A paper co-authored by Emily Day, “miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma”, has been selected as the cover of an upcoming issue of Genes & Development. The paper identifies a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor. The researchers used nanoparticles called spherical nucleic acids to safely deliver miR-182 across the blood-brain/blood-tumor barriers to reach tumor cells where they directly suppressed multiple oncogenes at once, increasing cancer cell death, reducing tumor growth, and improving overall survival. This approach offers a novel strategy for therapeutic intervention in GBM.
- UD top-ranked graduate degree programsU.S. News & World Report names University of Delaware graduate degree programs among the best in the nation
- Unveiling the renovated Design StudioFunded by donor support, UD’s Mechanical Engineering Design Studio now features 13,000 square feet and more than $2 million in manufacturing equipment
- How old is your brain?UD researchers find brain stiffness measurements are reliable predictors
- Unveiling the renovated Design StudioFunded by donor support, UD’s Mechanical Engineering Design Studio now features 13,000 square feet and more than $2 million in manufacturing equipment
- Fall 2024 News from Biomedical EngineeringThis has been an exceptionally productive year for our department. Read our latest newsletter to learn more.