Christopher Price joined UD’s biomedical engineering program in fall 2013 as an assistant professor. He is the co-principal investigator on a Department of Defense grant to study the highly targeted delivery of bisphosphonates, a class of traditional osteoporosis drugs, to prevent osteoarthritis from developing after acute traumatic injury. The research team’s preliminary work with animal studies revealed that the FDA approved bisphosphonate zoledronic acid (ZA) rescues post-traumatic osteoarthritis (PTOA), but adversely affects bone health. Price is studying if localized ZA injection can effectively prevent PTOA without hampering the bone’s natural development — research that could significantly affect osteoarthritis treatment. Price has also received a National Institute of Arthritis and Musculoskeletal and Skin Diseases grant in collaboration with others to study the effects of articular cartilage damage in osteoarthritis using spatiotemporal image correlation spectroscopy (STICS), a novel bioimaging technique. Changes in the fluid phase of cartilage are implicated in osteoarthritis so Price and his collaborators will use STICS to make direct real-time measurements of this phase. If successful, STICS will be the first bioimaging approach that provides direct real-time quantification of the fluid movement in cartilage and the changes of its solid matrix.
- Kiick and Price labs awarded R01 from the National Institutes of HealthThanks to a five-year, $3 million research grant, a team of UD engineers will develop approaches to improve delivery of therapeutics to treat post-traumatic osteoarthritis.
- Orthopedics in actionUD Engineering’s Jenni Buckley develops orthopedics curriculum for high school students.
- Doctoral Dissertation Defense – Mackenzie ScullyBME PhD Candidate Mackenzie Scully will be defending their dissertation: Engineering Cancer Cell Membrane-Wrapped Nanoparticles for Targeted Delivery of Cancer Therapeutics
- Doctoral Dissertation Defense – Zheng CaoDate: Thursday, September 7, 2023 Time: 9:30 am
- Doctoral Dissertation Defense – Wade StewartBME PhD Candidate Wade Stewart will be defending their dissertation: Implementation of static and dynamic culture substrates to control maturation of human induced pluripotent stem cell cardiomyocytes through tunable manipulation of topographical roughness and bulk stiffness.